Mechanism and origins of stereoselectivity in the cinchona thiourea- and squaramide-catalyzed asymmetric Michael addition of nitroalkanes to enones.
DOI Number:
10.1021/acs.joc.7b00521
Reaction Category:
Educt:
(E)-chalcone, nitromethane
Product:
(R)-4-nitro-1,3-diphenylbutan-1-one
Catalyst:
N-[3,5-bis(trifluoromethyl)phenyl]-N′- [(8α,9S)-10,11-dihydro-6′-methoxy- cinchonan-9-yl]-Thiourea
Cas No:
852913-19-0
Associated Product from Buchler GmbH:
Dihydroquinine Base
Cas No:
522-66-7