Buchler Glossary

Racemic Resolution

Racemic Resolution, also called optical resolution or chiral resolution, is a traditional widely-used process for the...

Racemate

A Racemate has equal amounts of left- and right-handed enantiomers of a chiral molecule.

Pseudoenantiomers

Cinchona alkaloids exist in nature as pseudoenantiomers, which allow Cinchona alkaloid-catalyzed reactions to provide...

Oxosulfonylation

Oxosulfonylation is a difunctionalization where oxo and sulfonyl groups are introduced in one step to construct...

Oxaziridination

Oxaziridines are generally formed by the action of a peracid on a combination of a carbonyl compound and an amine,...

Michael Addition

Michael addition (MA) is one of the most frequently used C-C bond-forming reactions in organic synthesis and is easily...

Mannich Reaction

The Mannich reaction is the aminoalkylation reaction, involving the condensation of an enolizable carbonyl compound...

Knoevenagel Reaction

Knoevenagel reaction is a condensation between an aldehyde or a ketone with an active hydrogen compound in the...

Isomerization

Isomerization is a chemical process by which a compound is transformed into any of its isomeric forms, i.e., forms...

Hydroxylation

Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound. Hydroxylation...

Hydrophosphonylation

Hydrophosphonylation refers to any reaction where addition across a double bond generates a phosphonate (RP(O)(OR')2)...

Hydrogenation

Hydrogenation is a reduction reaction which results in an addition of hydrogen (often as H2). If an organic compound...

Hydroarylation

Hydroarylation can be defined as the addition of an aryl group and a hydrogen atom across an unsaturated moiety...

Green Chemistry

Green chemistry is the design of chemical products and processes that reduce or eliminate the use or generation of...

Fluorination

Fluorination is for instance a replacement of one hydrogen atom within a molecule by fluorine. The incorporation of...

Epoxidation

Epoxidation is treatment where an electrophilic oxidizing agent is capable of introducing a single oxygen atom to...

Enantiomers

Enantiomers have identical chemical and physical properties and are indistinguishable from each other except for the...