Buchler Glossary
Racemic Resolution
Racemic Resolution, also called optical resolution or chiral resolution, is a traditional widely-used process for the...
Pseudoenantiomers
Cinchona alkaloids exist in nature as pseudoenantiomers, which allow Cinchona alkaloid-catalyzed reactions to provide...
Pictet–Spengler Reaction
Pictet–Spengler Reaction is a chemical reaction in which a β-arylethylamine undergoes condensation with an aldehyde or...
Oxosulfonylation
Oxosulfonylation is a difunctionalization where oxo and sulfonyl groups are introduced in one step to construct...
(Asymmetric) Oxohydroxylation
Asymmetric oxohydroxylation of α-alkyl enoates with potassium permanganate catalyzed by monocationic quaternary...
Oxaziridination
Oxaziridines are generally formed by the action of a peracid on a combination of a carbonyl compound and an amine,...
Morita–Baylis–Hillman Reaction
Morita–Baylis–Hillman Reaction is a carbon-carbon bond forming reaction between the α-position of an activated alkene...
Michael Addition
Michael addition (MA) is one of the most frequently used C-C bond-forming reactions in organic synthesis and is easily...
Mannich Reaction
The Mannich reaction is the aminoalkylation reaction, involving the condensation of an enolizable carbonyl compound...
Knoevenagel Reaction
Knoevenagel reaction is a condensation between an aldehyde or a ketone with an active hydrogen compound in the...
Isomerization
Isomerization is a chemical process by which a compound is transformed into any of its isomeric forms, i.e., forms...
Hydroxylation
Hydroxylation is a chemical process that introduces a hydroxyl group (-OH) into an organic compound. Hydroxylation...
Hydroxyalkylation
Hydroxyalkylation is an addition reaction that results in a hydroxyalkyl product.
Hydrophosphonylation
Hydrophosphonylation refers to any reaction where addition across a double bond generates a phosphonate (RP(O)(OR')2)...
Hydrogenation
Hydrogenation is a reduction reaction which results in an addition of hydrogen (often as H2). If an organic compound...
Hydroarylation
Hydroarylation can be defined as the addition of an aryl group and a hydrogen atom across an unsaturated moiety...
Henry Reaction (Nitroaldol Reaction)
The Henry reaction, also called Nitroaldol reaction, is a classic carbon–carbon bond formation reaction in organic...
Green Chemistry
Green chemistry is the design of chemical products and processes that reduce or eliminate the use or generation of...
Friedel-Crafts (FC) Reaction
The Friedel-Crafts (FC) reactions in organic chemistry are referred to two main types of reactions, known as...
Fluorination
Fluorination is for instance a replacement of one hydrogen atom within a molecule by fluorine. The incorporation of...
Epoxidation
Epoxidation is treatment where an electrophilic oxidizing agent is capable of introducing a single oxygen atom to...
Enantioselective Synthesis (Asymmetric Synthesis)
Enantioselective synthesis, also called asymmetric synthesis, is a form of chemical synthesis. It is defined by IUPAC...
Enantiomers
Enantiomers have identical chemical and physical properties and are indistinguishable from each other except for the...