The Wolff Rearrangement allows the generation of ketenes from α-diazoketones. During this  reaction an α-diazocarbonyl...

In the presence of a Cinchona squaramide-based catalyst, enolizable anhydrides react with alkylidene oxindoles to...

Biaryl compounds with axial chirality are very common in synthetic chemistry, especially in catalysis. Axially chiral...

The three-component reaction of aldehydes, primary aromatic amines, and phenols to produce α-aminobenzylphenols is...

The Barton–Zard reaction is a route to pyrrole derivatives via the reaction of a nitroalkene with an α-isocyanoacetate...

Cinchona alkaloids are complex small molecules containing five stereogenic centers, a basic quinuclidine nitrogen, a...

An Allylsilylation is performed between allylsilanes and aldehydes furnishes homo allyl alcohols. Using Cinchona...

The original reaction (1906) was a mixture of the reagents phenol, chloroform, and acetone in the presence of a sodium...

The Nobel Prize in Chemistry 2001 was divided, one half jointly to William S. Knowles and Ryoji Noyori "for their work...

The Nobel Prize in Chemistry 2021 was awarded jointly to Benjamin List and David W.C. MacMillan "for the development...

Specific Optical Rotation gives the angle of rotation of plane-polarized light by a certain compound at a certain...

Optical Rotation is the property displayed by chiral substances of rotating the plane of polarisation of polarised...

Nazarov Cyclization is one of the most versatile methods for the synthesis of cyclopentenones from vinyl ketones. For...

The diastereomeric ratio (dr) of the percent of one diastereomer in a mixture to that of the other diastereomer. For...

The diastereomeric excess (de) reflects the degree to which a sample contains one diastereomer in greater amounts than...

The ratio of the percent of one enantiomer in a mixture to that of the other. Enantiomeric ratio of 7:3 means for...

The Buchler chiral screening kit contains a set of slightly different Cinchona alkaloids in very high chemical purity....

Thorpe–Ziegler reaction is the intramolecular modification with a dinitrile as a reactant and a cyclic ketone as the...

Sulfenylation is the introduction of a sulfenyl group into a compound.

The Strecker amino acid synthesis, also known simply as the Strecker synthesis, is a method for the synthesis of amino...

The Sonogashira Reaction is a cross-coupling reaction used in organic synthesis to form carbon–carbon bonds. It...

Selenation is a reaction with a compound of selenium.

Reformatsky Reaction is an organic reaction which condenses aldehydes or ketones with α-halo esters using metallic...